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Lab Tests Explained Part 2: Lipid Profile – Cholesterol, LDL, HDL and Triglycerides Explained

Your lipid profile is one of the best early warnings for heart disease. Here is what each number means, the target ranges doctors use and how to improve your cholesterol.

Oats with berries, nuts, avocado and olive oil beside a blood sample tube
Oats with berries, nuts, avocado and olive oil beside a blood sample tube
In this article

    Heart disease is one of the leading causes of death in India, and it often strikes South Asians at a younger age. A lipid profile measures fats in your blood and is one of the simplest ways to spot rising heart risk years before symptoms appear.

    What the test measures

    • Total cholesterol: all the cholesterol in your blood.
    • LDL cholesterol ("bad" cholesterol): builds up in artery walls and causes blockages.
    • HDL cholesterol ("good" cholesterol): helps carry cholesterol away from arteries.
    • Triglycerides: fats that rise with excess calories, sugar, refined carbs and alcohol.
    • VLDL and non-HDL cholesterol (total minus HDL): additional risk markers.

    Commonly used target levels (mg/dL)

    TestDesirableBorderlineHigh
    Total cholesterolBelow 200200 – 239240 or more
    LDLBelow 100130 – 159160 or more
    TriglyceridesBelow 150150 – 199200 or more
    Non-HDLBelow 130130 – 159160 or more

    HDL: below 40 mg/dL in men or below 50 mg/dL in women is considered low; 60 mg/dL or more is considered protective.

    Your target depends on your risk

    There is no single "normal" LDL for everyone. People with diabetes, high blood pressure, smoking, a family history of early heart disease or a previous heart attack or stroke are usually given much lower LDL targets, often below 70 mg/dL or even lower. Indian cardiology groups generally recommend aggressive targets because South Asians have higher heart risk. Your doctor will set your goal based on your overall risk.

    Do you need to fast?

    Traditionally, a 9 to 12 hour fast was advised. Many guidelines now accept non-fasting samples for routine screening, but fasting may still be requested if triglycerides are high. Follow your lab's or doctor's instructions, and drink water as usual.

    How to improve your numbers

    • Cut refined carbs and sugar: maida, sweets and sugary drinks raise triglycerides.
    • Choose healthy fats: nuts, seeds, mustard or groundnut oil in moderation; limit vanaspati, deep-fried snacks and bakery items with trans fats.
    • Add fibre: oats, dal, vegetables, fruits and whole grains help lower LDL.
    • Move daily: at least 150 minutes a week of brisk activity raises HDL and lowers triglycerides.
    • Lose excess weight, especially around the waist.
    • Stop smoking and limit alcohol.

    When medicines are needed

    If lifestyle changes are not enough, or your risk is high, doctors may prescribe statins or other cholesterol-lowering drugs. These medicines are well studied and can significantly reduce heart attack and stroke risk. Never start or stop them on your own.

    How often to test

    Healthy adults are often advised to check their lipids every few years from their twenties or thirties, and more often if they have risk factors or are on treatment.

    Lab Tests Explained: the full series

    Related reads: Blood sugar levels and HbA1c · Thyroid tests · Vitamin D test · Uric acid

    Disclaimer: This article is for general information only and is not medical advice. Reference ranges vary between laboratories, so always read your report against the range printed on it and discuss results with a qualified doctor.

    Written by Raj

    Founder & Editor

    I write HorizonDesk: practical, no-hype articles on technology, money, business and the vehicles we drive. Everything here is something I’ve researched, tested or wanted explained clearly myself.